Thursday, September 21, 2017

First Day of Fall

http://www.bbc.com/news/science-environment-41311087 This is an article written to commemorate the lecture given by Francis Crick 60 years ago for the Society for Experimental Biology at University College, London, predicting the way the genetic code is used to produce proteins.How does the cell get from the linear sequence of bases to the three-dimensional structure of proteins. It still amazes me that this was determined based on the scanty knowledge that was available and the relatively primitive technologies (compared with today's.



Crick's 'central dogma' diagram (c) Wellcome Library

http://www.philly.com/philly/health/health-news/penn-scientists-probe-the-mysterious-relationship-between-sleep-deprivation-and-depression-20170922.html An article from the Philly Inquirer about research findings at Penn about sleep deprivation's curative powers over depression. Research has shown that from 3-4 hours of sleep followed by 21 to 36 hours of wakefulness eliminated feelings of depression in 50% of people in 66 studies that were analyzed. This work was published in the Journal of Clinical Psychiatry. The problem was that after one good night's sleep, the depression returned.

https://www.nytimes.com/2017/09/21/business/monsanto-dicamba-weed-killer.html?mcubz=1&_r=0
This is a NYT Business Section article about dicamba, a weed killer marketed by Monsanto. Lawsuits are being initiated against the company because farmers who have not bought Monsanto's genetically modified dicamba-resistant seeds are claiming that their crops are being damaged by dicamba drifting sometimes large distances. This is a typical strategy, to develop these resistant seeds and then to spray weed-killers, both marketed by Monsanto. It seems like a viscous cycle, because as weeds become resistant to the herbicides, it requires more pesticide use to kill them. Drift problems have made it impossible to control where herbicides wind up.


https://www.nytimes.com/2017/09/21/sports/aaron-hernandez-cte-brain.html?mcubz=1 This is a NYT article about the extremely unfortunate case of Aaron Hernandez, former Patriot's linebacker, found guilty of murder, who committed suicide in prison in April. Studies of his brain have revealed CTE, or Chronic Traumatic Encephalopathy. Hernandez was 27 but his the degenerative brain damage was equivalent to the brains of players beyond their 60's. Research has been recently revealed at Boston University showing that players who began playing tackle football before the age of 12 developed more cognitive and behavioral problems as adults later in life than those who started playing after the age of 12.







https://www.nytimes.com/2017/09/09/opinion/sunday/trump-epa-pruitt-science.html?mcubz=0
This is an editorial from NYT about the consistent trend in the current administration to terminate work on important environmental issues such as mountaintop removal of coal and reducing carbon emissions to name only two consequential issues among a multitude. In additional, the lack of appointment of key scientific advisors to various departments and appointment of persons lacking in scientific credentials to key offices shows evident disdain for science and scientific knowledge and its contributions.




https://www.nytimes.com/2017/09/21/nyregion/staten-island-bat-watchers-research.html?mcubz=0&_r=0 This is an article on bat researchers in Freshkills Park on Staten Island. Not surprisingly, these researchers are nocturnal, as are their quarry. Wearing anabat detectors strapped to their wrists, seniors at the College of Staten Island along with wildlife biologists, are netting bats in order to study them. The first published study of bats was in 2016 and the work being compiled is some of the first systematic data collected on bats in NYC. White nose disease, caused by a fungus has decimated the bat population across North America on a massive scale. After netting the bats, the researchers are fitted with tracking bands, weighed and checked for fungus.

iStock_sleep-exhausted-3x2

Friday, September 1, 2017

After Harvey

http://www.medicalnewstoday.com/articles/318713.php?utm_source=TrendMD&utm_medium=cpc&utm_campaign=Medical_News_Today_TrendMD_1
This is from Medical News Today newsletter about research published in the journal Neuron on new treatments for depression, going beyond SSRIs like Prozac and Zoloft. SSRIs prevent serotonin from being reabsorbed at the synapse by the neuron that secreted it after it does its job on the second neuron. Researchers at the Rockefeller University researched the effects of serotonin on cells in the dentate gyrus using a technique called translating ribosome affinity purification and found a receptor important for SSRIs long-term effects.
Brain in a pill.

http://www.npr.org/sections/goatsandsoda/2017/09/02/547892623/triple-threat-new-pneumonia-is-drug-resistant-deadly-and-contagious An npr report about drug-resistant pneumonia (klebsiella pneumoniae) found in a hospital in Hangzhou, China, as reported in the Lancet Infectious Diseases, which was resistant to the toughest antibiotics. Similar strains have been isolated from a case in Nevada, which was resistant to 26 antibiotics but the Chinese stains are deemed "hypervirulent.




https://www.statnews.com/2017/08/29/fat-nutrition-study/ From STAT News, a report of a study called PURE (Prospective Urban Rural Epidemiology recording the eating habits of 135,000 adults in 18 countries. People with the highest intake of dietary fat (35%) were 23% less likely to die during the study period than those whose diet was 10% fat. Findings for carb consumption went in the opposite direction, those whose diet was 77% carb were more likely to die, while those with a 46% carb diet were the least likely. These results were published in the Lancet.


http://www.philly.com/philly/health/health-news/what-diabetic-mice-can-teach-us-about-keeping-teeth-healthy-20170901.html  From the Inquirer a report on a study of dental health done at Penn Dental which looked at the oral microbiomes of people with diabetes. Typically, unmanaged diabetes causes changes to the bacteria in the mouth, leading eventually to inflammation of the gums and bone loss. They compared mouth bacteria from diabetic mice to bacteria from normal mice (former were worse) and then transferred mouth bacteria from diabetic mice to germ free mice and found that diabetic mouth bacteria caused 42% more bone loss than bacteria from normal mice.

https://www.washingtonpost.com/news/answer-sheet/wp/2017/08/28/teacher-shortages-affecting-every-state-as-2017-18-school-year-begins/?utm_term=.f70ec832f89 Article from the WashPost describing US Dept of Education data of states where there are teacher shortages shows that there are teacher shortages in every state.  Shortages have been in existence since data began to be collected 25 years ago but the problem has been exacerbated recently. The teacher education enrollment dropped 35% from 2009 to 2014. There is also an "acute shortage" in substitute teachers.


https://www.nytimes.com/2017/09/06/learning/announcing-a-new-monthly-feature-whats-going-on-in-this-graph.html?mcubz=1 This is an announcement of a new monthly feature in the NYT partnering with the American Statistical Association to produce WGOITGraph? They will offer a NYT graphic and pose questions to students. The graphs will remain online and teachers can use them in the classroom. Students will also be able to post comments.

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